Orlando (CNN)The massive search for a man suspected of killing his pregnant girlfriend and gunning down an Orlando police officer has expanded beyond Florida, police said Tuesday.

Markeith Loyd has been on the run since Monday morning when police say he killed Master Sgt. Debra Clayton as she tried to confront the murder suspect outside a Walmart.

The manhunt for Loyd has already led to several injuries and the death of Orange County Sheriff's Deputy 1st Class Norman Lewis, who died in a motorcycle crash while searching for him.

As hundreds of law enforcement officers scramble to find a man called "armed and extremely dangerous," here are the latest developments:Authorities increased the reward for information leading to Loyd's arrest to $100,000, Orlando police Chief John Mina said Tuesday.

"The Orlando Police Department, the Orange County Sheriff's Office, the FBI, the Florida Department of Law Enforcement, homeland security, the U.S. marshals -- everyone is working to capture him," he said earlier.Clayton's death was the latest blow for the Orlando Police Department, which is still reeling from the June massacre at the Pulse nightclub that left 49 people dead.

"Unfortunately we still have officers that are struggling with the Pulse tragedy," the police chief said. "It's been a tough seven or eight months for us."

Clayton responded moments after the mass shooting at the club, police spokeswoman Michelle Guido said.

"Like many of other officers here, she was a first responder that had to go to Pulse in the early morning hours to assist," Mina said.After the shooting, Loyd fled in a car and fired shots at another officer, police said. That officer was not seriously injured.

The suspect then abandoned the first vehicle and carjacked another one. He ditched that second vehicle shortly afterward and ran into an apartment complex, Mina said.

It's unclear where he is now. But a "be on the lookout" alert has been sent nationwide, which is standard procedure with Florida murder suspects, said Guido, the police spokeswoman.

"I believe there have been people out there helping him all along," Mina said. "If we find out about those people, we will criminally charge them."

He said Loyd would be charged with first-degree murder of a law enforcement officer and attempted murder of the officer at whom he fired.During his confirmation hearing Tuesday on Capitol Hill, the US attorney general nominee, Sen. Jeff Sessions of Alabama, spoke about the dual tragedies that happened on National Law Enforcement Appreciation Day.

"Sadly, on that day, we lost two of our brave officers," Sessions said.

He said Clayton and Lewis "dedicated their lives to keeping their communities safe, and we should remember their service and keep them and their families in our prayers."